Further studies follow.  The full research write up is below:

Introduction

The more vigorously we live our life, the more we strain our cells and drain our energy. This is a problem because when energy is compromised, our physical and mental performance declines. We are motivated to find solutions to this problem.  Our research seeks nutritional formulations for energy to revivify body and mind. This naturally leads us to the mitochondria, and the biochemical reactions that power our cells.

Nutritional Intervention For
Optimizing Mitochondrial Performance

Anta Badulescu, Kamilia Talipova, Shuk Yee Ngan, and Frank Merante

Background

Life exposes us to various stresses, both mental and physical. These stresses place demands on our cellular metabolic reserves.  In the face of these stresses, our bodies mount a coordinated response to restore balance.

By providing key metabolic intermediates to the cellular mitochondria, optimal cellular homeostasis and metabolic replenishing molecules are provided.  This is proposed to support and augment energy, maintenance of cellular reserves, and aerobic cellular function.

The purpose of this study was to investigate how performance under exercise stress can be moderated. We wanted to determine if exercise work capacity and recovery, can be improved through the administration of a synergistic blend of key metabolic nutrients, which includes Vitamin C and metabolic intermediates: Citrate, Malate and Pyruvate (The Mitronite Formulation).

By examining performance under exercise stress, we create conditions that are more extreme than the typical stresses of daily life.  Therefore, we believe the results my provide insight into both exercise performance and general well being.

We collaborated with the Seneca College School of Biological Sciences and Applied Chemistry on an in vivo kinesiology-testing model to demonstrate the performance enhancement characteristics of Mitronite.

This project was funded by Project funded by Seneca’s Applied Research Fund (ARF).

Methods

• A total of 14 participants, from 18-62 years in age, volunteered to complete 2 training sessions;
  • a control session (“un-dosed”),  and
  • a ”dosed” session where the Mitronite Nutrients were taken before and during exercise..
• The exercises consisted of barbell squats, deadlift, and floor press.
• Each work set consistent of a 20 second max effort sprint, followed by 90 seconds of rest.
• Each exercise was performed for a total of 10 sets each, for a total of 30 sets. 
• After the first session was completed, the second session was conducted 2 weeks later.

Data Collection

The following data we collected and analyzed:

• The number of repetitions completed for each exercise work set.
• The repetition at which the onset of exercise induced muscle burn began, for each set.
• The peak burn severity of of the exercise induced muscle burn as self reported on a scale from 1-5 at the conclusion of each set.
• In addition, sweat samples were collected to detect and analyze metabolites, minerals, other trace elements (data not shown). 

Results

Exercise Work Capacity (EWC) in un-dosed (without Mitronite) vs. dosed (with Mitronite) conditions was analyzed from three different perspectives. EWC as represented by:

1. The number of repetitions completed for each exercise work set,
2. The rep at which athletes experienced the onset of exercise induced muscle burn (Onset of Burn), and 
3. The Peak Burn Severity (PBS) experienced by athletes at the conclusion of each work set.

Results indicated that the Mitronite Nutrients created a significant positive impact on Exercise Work Capacity.